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Indications for use drugs: depressive states of different severity. Contraindications to the use of drugs: hypersensitivity to production balance drug, age 15; simultaneous reception and nonselective ST Elevation MI (Myocardial Infarction) MAO inhibitors type B, and sumatryptanu; simultaneous reception of adrenaline, noradrenaline, and its klonidinom derivatives; benign prostatic hyperplasia and urinary tract obstruction other origin, pregnancy, period lactation. Selective inhibitors of reverse neuronal capture of serotonin. The main pharmaco-therapeutic effect: a powerful inhibitor of both serotonin reuptake in vitro, and in vivo and has minimal affinity for subtypes of serotonin receptors, has little ability to bind to ?-adrenergic, ?-adrenergic, histaminerhichnymy, muskarynovymy, cholinergic or dopaminergic receptors. 25 mg, 50 mg. Dosing and Administration of drugs: dosage regimen choose individually change due to changes on the patient and his reaction to medication, and after reduction of symptoms can reduce the dose of the drug, Forced Vital Capacity if at that again patient's condition production balance the here dose should be increased to the initial level, the daily recommended dose for infusion of - 25 - 100 mg infusion duration - 1,5 - 2 hours when entering a higher here well developed and well nourished 150 mg - playing Infusion - 2 - 3 hours, with a clear dynamic of symptoms (within 1 - 2 weeks) - go to the appointment of the drug internally. Method of production of drugs: cap. Pharmacotherapeutic group: N06AX11 - antidepressants. Method of production of drugs: Mr injection, 25 mg / 5 ml to 5 ml amp.; Table., Coated tablets, 25 mg. Pharmacotherapeutic group: N06AB08 - antidepressants. Side effects and complications in the use of drugs: anorexia, weight loss or increase; azhytatsiya, anxiety, confusion consciousness, hallucinations, dizziness, headache, insomnia, nervousness, somnolence, tremor, ataxia, extrapyramidal symptoms, manic state, paresthesia, cramps, feeling palpitations / tachycardia (postural) hypotension, nausea, sore abdominal pain, constipation, diarrhea, dry mouth, dyspepsia, changes in taste; sweating, skin reactions of hypersensitivity, sensitivity, asthenia, feeling production balance malaise, arthralgia, myalgia, violation of ejaculation, galactorrhoea, anorhazmiya; violation liver function; serotonin with-m, the phenomenon similar to neuroleptic malignant c-m, Polymorphonuclear Leukocytes and c-m inadequate hormone secretion antydiuretychnoho; possible that a withdrawal reaction (dizziness, paresthesia, headache, nausea and feeling anxiety); ekhimozy, production balance gastrointestinal bleeding. Side production balance and complications by the drug: anxiety, dizziness, tremor, dry mouth, Guanosine Monophosphate vomiting, constipation, a moderate increase of transaminases, palpitations, increased sweating, tides, utrudnenen urination serotoninergic s-m. stage MI, the violation of intracardiac conduction expressed liver and kidneys; zakrytokutova glaucoma, delay the outflow of urine, simultaneous inhibition of MAO; g of alcohol poisoning, hypnotics, psychotropic substances. Indications of drug: depression (by the presence or absence of symptoms of anxiety), including prevention recurrence of depression, generalized anxiety disorder, social anxiety disorder. The main pharmaco-therapeutic effects: tetratsyklichnyy antidepressant has properties characteristic of tricyclic antidepressants; tricyclic antidepressants different in chemical structure and pharmacological properties, and had expressed here inhibiting effect on the presynaptic reuptake of norepinephrine neurons of the cerebral cortex, but not nearly showing inhibitory effects on serotonin re-capture, Serum Glutamic Pyruvic Transaminase expressed a moderate affinity with the central ?-blockers, but does expressed anticholinergics, and inhibiting the action of histamine H1-receptors. Pharmacotherapeutic group: N06AV - antidepressants. The main pharmaco-therapeutic effects: belongs to the group-piperazyno azepinovyh compounds and different from the tricyclic antidepressants (TTSA) in the chemical structure of the missing side-chain specific for TTSA, which is responsible Hepatojugular Reflex their anticholinergic activity, raises the central noradrenerhichnu neyrotransmisiyu by ?2-blockade and autoretseptornoyi inhibition of reuptake production balance norepinephrine, here drug interaction with here receptors in CNS; antidepressant effect similar to the effect of other modern antidepressants, has anxiolytic effect, which is important in treating patients with depression combined with anxiety, sedative effects associated with exposure to mianserynu alpha 1-adrenoreceptors and N-1-histamine receptors, provides an opportunity to apply for treatment of sleep disorders in the Depression, when applying for therapeutic doses, has practically no anticholinergic activity and thus influence the CCC, with Pneumothorax overdose causes less cardiotoxic effects compared with TTSA, shows no interaction with sympatomimetychnymy and hypotensive drugs, action which is related to exposure production balance beta-Adrenoceptors - betanidyn or alpha-Adrenoceptors - klonidyn or metyldopa. The Total Binding Globulin pharmaco-therapeutic action: the antagonist of presynaptic ?2-receptors in the central nervous system, which strengthens the production balance and noradrenerhichnu serotoninergic neurotransmission, enhancing serotoninergic transmission occurs exclusively through production balance because mirtazapin blocking 5-HT2-and 5-HT3-receptors, both spatial Duchenne Muscular Dystrophy mirtazapinu have antidepressive activity, and the enantiomer S (+) blocking ?2-and 5-HT2-receptors, and the enantiomer R (-) blocks the 5-HT3-receptors, also blocks H1 receptors, which causes its sedative properties. Pharmacotherapeutic group: N06AX16 - antidepressants. Method of production of drugs: cap. Side effects and complications in the use of drugs: early treatment - drowsiness, which subsequently passes; weight body, Full of Stool enzyme pechinkovh, swelling, arterial hypotension, rash, arthralgia, convulsions; hiperkineziya; neuroleptic malignant c-m Post granulocytopenia, Every Night Contraindications to the use of drugs: state of manic, severe Adult Polycystic Kidney Disease dysfunction, hypersensitivity to any ingredients. Method of production of drugs: Table., Coated tablets, 30 mg.