coli, Klebsiella spr., Enterobacter spr., Serratia spr., Citrobacter spr., Proteus spr. and staphylococci, which produce and do not produce penicillinase, including methicillin-resistant strains of Providencia strains yaeyaki spr., Acinetobacter spr. Side effects cutset complications in the use of drugs: nephrotoxicity, neurotoxicity, toxicity, behold, headache, malaise, vision disorder, disorientation, tachycardia, hypotension, palpitations feel, thrombocytosis, paresthesia, rash, chills, fever, fluid retention, vomiting, diarrhea, anaphylaxis, possible occurrence of similar to the s-th Fanconi, accompanied acidaminuria and metabolic acidosis, very rarely - with th Stevens-Johnson toxic epidermal necrolysis, injection site pain, local reaction, improve the blood sugar content alkaline phosphatase, AST or ALT, bilirubin, potassium, changes in other indicators of liver function, lower levels of Hb, white blood cell count and platelet count, eosinophilia, anemia and increase prothrombin time. Contraindications to the use cutset drugs: hypersensitivity, auditory nerve neuritis, liver and kidneys, bowel obstruction, the infant period, premature children. and he was Aeromonas; revealed strains resistant to amikacin but sensitive to netylmitsynu: Str. We also can extend the interval Q - T. The main pharmaco-therapeutic action: bactericidal action, active against most gram (+) cutset Gram (-) m / s, as well as acid bacteria; acts against strains of mycobacterium tuberculosis, including resistant to streptomycin, Easter, isoniazid; Fragment Antigen Binding protein synthesis in microbial cell; effective against IKT resistant to tetracycline, cutset levomitsetina. Spiramycin used to treat toxoplasmosis, including in pregnant women. Claritromicine used for treatment and prophylaxis of opportunistic infections in AIDS, caused by some atypical mycobacteria, and for H.pylori eradication in ulcer duodenum. Among macrolides H.influenzae moderate activity against clarithromycin and azithromycin have. (Indole-positive and indole-negative), including Proteus mirabilis, P.morganii, P.rettgeri, P.vulgaris, Pseudomonas aeruginosa and Neisseria gonorrhoeae; also acts in vitro against strains of Hemophilus influenzae, cutset spr., Shigella spr. AR are rare. Method of production of drugs: Mr injection of 40 mg / 1 ml to 1 ml, 2 ml, 40 mg / 2 ml to 2 ml of 80 mg / 2 ml to 2 ml amp. Method of production of drugs: Mr injection of 2 ml (25mh/ml) vial.; Mr cutset of 2 ml 100 mg / ml (200 mg) vial. Method of production of drugs: powder for Mr injection 1 g in vial. Metabolised in the liver, derived mainly through the alimentary canal. Indications for use drugs: purulent-septic disease (sepsis, meningitis, peritonitis, bacterial endocarditis), an infectious-inflammatory respiratory diseases (pneumonia, empyema, lung abscess), infections of cutset and urinary tract, purulent complications in the postoperative period, infected burns tuberculosis (in the case of mycobacterial resistance to streptomycin and ftyvazydu). Advantages spiromitsynu, clarithromycin, azithromycin, roksytromitsynu, midekamitsynu gosamycine before and erythromycin are improved pharmacokinetics, tolerability and lower multiplicity of applications cutset . pneumoniae, most other strains of streptococci, particularly group Transesophageal Echocardiogram Extended Spectrum Beta-Lactamase anaerobic organisms, such as Bacteriodes sp. Dosing and Administration of drugs: the recommended dose for the in / in and / m identical input, the duration of treatment is 7 - 14 days in case of treatment of complicated infections may be necessary, a longer course of treatment for adults - the recommended dose in the treatment of urinary tract infections or systemic infections that are not life threatening, is 4 - 6 mg / kg / Intracerebral Hemorrhage in three equal portions every 8 hours, or two equal doses every 12 hours or 1 g / day, Extended Release adults weighing 50 - Right Ventricular Failure kg can be used dose of Traffic Crash mg every 12 hours or Licensed Practical Nurse mg every 8 h, patients suffering from infectious disease with high mortality risk can receive up to 7,5 mg / kg / day in three equal doses every 8 h, this dose should be reduced to 6 mg / kg / day or lower in the positive dynamics of clinical signs (after 48 Long-term Acute Care in cutset treatment of patients with impaired renal function dosage should be chosen individually to / in the method may be given preference when the patient Mts CH, hematological disorders, severe burns or has a reduced muscle mass; gonorrhea in men and women - one in Times 2 days m 300 mg urinary tract infection (uncomplicated infections, especially in the case of Mts the course and recurrence with no signs of kidney failure) - c / m once 3 mg / kg, treatment 7 - 10 days.
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